Topoisomerase-targeting antitumor drugs: mechanisms of cytotoxicity and resistance.

Liu, L F; D'Arpa, P

Liu, L F; D'Arpa, P.

Important Adv Oncol ; : 79-89, 1992.

Article in En | MEDLINE | ID: mdl-1316311

Subject(s)

Antineoplastic Agents/pharmacology; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Animals; Camptothecin/pharmacology; Cell Cycle/drug effects; Cell Death/drug effects; DNA Damage; DNA, Neoplasm/metabolism; DNA, Superhelical/metabolism; Drug Resistance; Gene Expression Regulation, Enzymologic; Humans; Tumor Cells, Cultured/drug effects; Tumor Cells, Cultured/enzymology

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Collection: 01-internacional Database: MEDLINE Main subject: Topoisomerase I Inhibitors / Topoisomerase II Inhibitors / Antineoplastic Agents Limits: Animals / Humans Language: En Journal: Important Adv Oncol Year: 1992 Document type: Article

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