Effector stage CC chemokine receptor-1 selective antagonism reduces multiple sclerosis-like rat disease.

Eltayeb, Sana; Sunnemark, Dan; Berg, Anna-Lena; Nordvall, Gunnar; Malmberg, Asa; Lassmann, Hans; Wallström, Erik; Olsson, Tomas; Ericsson-Dahlstrand, Anders

Eltayeb, Sana; Sunnemark, Dan; Berg, Anna-Lena; Nordvall, Gunnar; Malmberg, Asa; Lassmann, Hans; Wallström, Erik; Olsson, Tomas; Ericsson-Dahlstrand, Anders.

Affiliation

Eltayeb S; Neuroimmunology Unit, Department of Medicine, Karolinska Institutet, SE-171 76 Stockholm, Sweden.

J Neuroimmunol ; 142(1-2): 75-85, 2003 Sep.

Article in En | MEDLINE | ID: mdl-14512166

Subject(s)

Chemokines, CC/metabolism; Encephalomyelitis, Autoimmune, Experimental/immunology; Encephalomyelitis, Autoimmune, Experimental/prevention & control; Multiple Sclerosis/immunology; Multiple Sclerosis/prevention & control; Receptors, Chemokine/antagonists & inhibitors; Receptors, Chemokine/biosynthesis; Animals; Cell Migration Inhibition; Chemokines, CC/antagonists & inhibitors; Disease Models, Animal; Drug Administration Schedule; Encephalomyelitis, Autoimmune, Experimental/pathology; Female; Immunosuppressive Agents/administration & dosage; Immunosuppressive Agents/adverse effects; Injections, Subcutaneous; Lymphoproliferative Disorders/chemically induced; Multiple Sclerosis/pathology; Myelin Proteins; Myelin-Associated Glycoprotein/toxicity; Myelin-Oligodendrocyte Glycoprotein; Nitriles/administration & dosage; Nitriles/adverse effects; Piperazines/administration & dosage; Piperazines/adverse effects; Rats; Receptors, CCR1

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Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Chemokine / Chemokines, CC / Encephalomyelitis, Autoimmune, Experimental / Multiple Sclerosis Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Neuroimmunol Year: 2003 Document type: Article

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