Expression of drug-metabolizing enzymes, nuclear transcription factors and ABC transporters in Caco-2 cells.

Borlak, J; Zwadlo, C

Borlak, J; Zwadlo, C.

Affiliation

Borlak J; Fraunhofer Institute of Toxicology and Experimental Medicine, Center for Drug Research and Medical Biotechnology, Nicolai-Fuchs-Str. 1 D-30659, Hannover, Germany. borlak@item.fraunhofer.de

Xenobiotica ; 33(9): 927-43, 2003 Sep.

Article in En | MEDLINE | ID: mdl-14514442

Subject(s)

ATP-Binding Cassette Transporters/metabolism; Cell Nucleus/metabolism; Mixed Function Oxygenases/biosynthesis; Transcription Factors/metabolism; Aged; Caco-2 Cells; Culture Media; Cytochrome P-450 Enzyme System/biosynthesis; DNA, Complementary/biosynthesis; Epoxide Hydrolases/metabolism; Humans; In Vitro Techniques; Liver/drug effects; Liver/enzymology; Male; Middle Aged; Oligonucleotide Probes; Polychlorinated Biphenyls/pharmacology; RNA/biosynthesis; Reverse Transcriptase Polymerase Chain Reaction; Testosterone/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Cell Nucleus / ATP-Binding Cassette Transporters / Mixed Function Oxygenases Limits: Aged / Humans / Male / Middle aged Language: En Journal: Xenobiotica Year: 2003 Document type: Article

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