Human mitochondria in health, disease, ageing and cancer.
J Appl Genet
; 42(1): 65-71, 2001.
Article
in En
| MEDLINE
| ID: mdl-14564065
ABSTRACT
In every human cell there are hundreds of mitochondria, which are required for oxidative phosphorylation as well as many other metabolic processes. Each mitochondrion contains approximately 5 mitochondrial DNA molecules. These circular DNAs of 16.5 kb in size contain only 39 genes. Mutations in mitochondrial DNA are responsible for many diseases. Alterations in these molecules may also play a role in ageing and in tumour formation.
Search on Google
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
J Appl Genet
Year:
2001
Document type:
Article