Transforming growth factor-beta production and myeloid cells are an effector mechanism through which CD1d-restricted T cells block cytotoxic T lymphocyte-mediated tumor immunosurveillance: abrogation prevents tumor recurrence.

Terabe, Masaki; Matsui, So; Park, Jong-Myun; Mamura, Mizuko; Noben-Trauth, Nancy; Donaldson, Debra D; Chen, Wanjun; Wahl, Sharon M; Ledbetter, Steven; Pratt, Bruce; Letterio, John J; Paul, William E; Berzofsky, Jay A

Terabe, Masaki; Matsui, So; Park, Jong-Myun; Mamura, Mizuko; Noben-Trauth, Nancy; Donaldson, Debra D; Chen, Wanjun; Wahl, Sharon M; Ledbetter, Steven; Pratt, Bruce; Letterio, John J; Paul, William E; Berzofsky, Jay A.

Affiliation

Terabe M; Molecular Immunogenetics and Vaccine Research Section, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

J Exp Med ; 198(11): 1741-52, 2003 Dec 01.

Article in En | MEDLINE | ID: mdl-14657224

Subject(s)

Antigens, CD1/immunology; Bone Marrow Cells/immunology; Neoplasms, Experimental/immunology; T-Lymphocytes, Cytotoxic/immunology; Transforming Growth Factor beta/biosynthesis; Animals; Antigens, CD1d; Cell Division/immunology; Female; Flow Cytometry; Immunophenotyping; Interleukin-13/immunology; Mice; Mice, Inbred BALB C; Mice, Knockout; Neoplasms, Experimental/pathology; Recurrence; Tumor Cells, Cultured

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bone Marrow Cells / T-Lymphocytes, Cytotoxic / Transforming Growth Factor beta / Antigens, CD1 / Neoplasms, Experimental Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Exp Med Year: 2003 Document type: Article

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