Colonic dendritic cells, intestinal inflammation, and T cell-mediated bone destruction are modulated by recombinant osteoprotegerin.

Ashcroft, A J; Cruickshank, S M; Croucher, P I; Perry, M J; Rollinson, S; Lippitt, J M; Child, J A; Dunstan, C; Felsburg, P J; Morgan, G J; Carding, S R

Ashcroft, A J; Cruickshank, S M; Croucher, P I; Perry, M J; Rollinson, S; Lippitt, J M; Child, J A; Dunstan, C; Felsburg, P J; Morgan, G J; Carding, S R.

Affiliation

Ashcroft AJ; Academic Unit of Haematology and Oncology, School of Medicine, University of Leeds, Leeds, United Kingdom.

Immunity ; 19(6): 849-61, 2003 Dec.

Article in En | MEDLINE | ID: mdl-14670302

Subject(s)

Adjuvants, Immunologic/pharmacology; Bone and Bones/drug effects; Dendritic Cells/drug effects; Glycoproteins/pharmacology; Inflammation/drug therapy; Animals; Bone Diseases, Metabolic/drug therapy; Bone Diseases, Metabolic/genetics; Bone Diseases, Metabolic/immunology; Bone and Bones/immunology; Carrier Proteins/metabolism; Colon/drug effects; Colon/immunology; Dendritic Cells/immunology; Homeodomain Proteins/genetics; Homeodomain Proteins/metabolism; Inflammation/immunology; Interleukin-2/genetics; Interleukin-2/immunology; Membrane Glycoproteins/metabolism; Mice; Mice, Transgenic; Osteoprotegerin; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Receptors, Cytoplasmic and Nuclear; Receptors, Tumor Necrosis Factor; T-Lymphocytes/drug effects; T-Lymphocytes/immunology

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Collection: 01-internacional Database: MEDLINE Main subject: Bone and Bones / Dendritic Cells / Glycoproteins / Adjuvants, Immunologic / Inflammation Type of study: Prognostic_studies Limits: Animals Language: En Journal: Immunity Year: 2003 Document type: Article

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