Pharmacologic inhibition of intracellular caspases after myocardial infarction attenuates left ventricular remodeling: a potentially novel pathway.

Yarbrough, William M; Mukherjee, Rupak; Escobar, G Patricia; Sample, Jeffrey A; McLean, Julie E; Dowdy, Kathryn B; Hendrick, Jennifer W; Gibson, William C; Hardin, Amy E; Mingoia, Joseph T; White, Patrick C; Stiko, Ann; Armstrong, Robert C; Crawford, Fred A; Spinale, Francis G

Yarbrough, William M; Mukherjee, Rupak; Escobar, G Patricia; Sample, Jeffrey A; McLean, Julie E; Dowdy, Kathryn B; Hendrick, Jennifer W; Gibson, William C; Hardin, Amy E; Mingoia, Joseph T; White, Patrick C; Stiko, Ann; Armstrong, Robert C; Crawford, Fred A; Spinale, Francis G.

Affiliation

Yarbrough WM; Division of Thoracic Surgery, Medical University of South Carolina, Charleston 29425, USA.

J Thorac Cardiovasc Surg ; 126(6): 1892-9, 2003 Dec.

Article in En | MEDLINE | ID: mdl-14688702

Subject(s)

Caspase Inhibitors; Enzyme Inhibitors/pharmacology; Myocardial Infarction/physiopathology; Myocardium/enzymology; Ventricular Remodeling/physiology; Animals; Apoptosis; Caspases/metabolism; Caspases/physiology; Coronary Circulation; Echocardiography; Myocardial Contraction; Myocardial Infarction/diagnostic imaging; Myocardial Infarction/enzymology; Swine; Ventricular Function, Left

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Collection: 01-internacional Health context: 6_ODS3_enfermedades_notrasmisibles Database: MEDLINE Main subject: Ventricular Remodeling / Enzyme Inhibitors / Caspase Inhibitors / Myocardial Infarction / Myocardium Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Thorac Cardiovasc Surg Year: 2003 Document type: Article

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