Epidermal growth factor activates m-calpain (calpain II), at least in part, by extracellular signal-regulated kinase-mediated phosphorylation.

Glading, A; Bodnar, R J; Reynolds, I J; Shiraha, H; Satish, L; Potter, D A; Blair, H C; Wells, A

Glading, A; Bodnar, R J; Reynolds, I J; Shiraha, H; Satish, L; Potter, D A; Blair, H C; Wells, A.

Affiliation

Glading A; Departments of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA.

Mol Cell Biol ; 24(6): 2499-512, 2004 Mar.

Article in En | MEDLINE | ID: mdl-14993287

Subject(s)

Calpain/metabolism; Epidermal Growth Factor/pharmacology; Mitogen-Activated Protein Kinases/metabolism; Amino Acid Substitution; Animals; Base Sequence; Binding Sites; Calcium/metabolism; Calpain/chemistry; Calpain/genetics; Cell Line; Cell Movement; DNA, Complementary/genetics; Enzyme Activation/drug effects; Humans; In Vitro Techniques; MAP Kinase Signaling System; Mice; Mutagenesis, Site-Directed; Phosphorylation; Recombinant Proteins/chemistry; Recombinant Proteins/genetics; Recombinant Proteins/metabolism; Serine/chemistry

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Calpain / Mitogen-Activated Protein Kinases / Epidermal Growth Factor Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Mol Cell Biol Year: 2004 Document type: Article

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