Recombinant monoclonal thyrotropin-stimulation blocking antibody (TSBAb) established from peripheral lymphocytes of a hypothyroid patient with primary myxedema.

Moriyama, K; Okuda, J; Saijo, M; Hattori, Y; Kanamoto, N; Hataya, Y; Matsuda, F; Mori, T; Nakao, K; Akamizu, T

Moriyama, K; Okuda, J; Saijo, M; Hattori, Y; Kanamoto, N; Hataya, Y; Matsuda, F; Mori, T; Nakao, K; Akamizu, T.

Affiliation

Moriyama K; Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan.

J Endocrinol Invest ; 26(11): 1076-80, 2003 Nov.

Article in En | MEDLINE | ID: mdl-15008244

Subject(s)

Antibodies, Monoclonal/blood; Hypothyroidism/immunology; Immunoglobulins, Thyroid-Stimulating/blood; Myxedema/immunology; Animals; Antibodies, Monoclonal/chemistry; Antibodies, Monoclonal/pharmacology; Base Sequence; Cricetinae; Graves Disease/blood; Graves Disease/immunology; Humans; Hypothyroidism/blood; Immunoglobulin Heavy Chains/immunology; Immunoglobulin Light Chains/immunology; Immunoglobulins, Thyroid-Stimulating/chemistry; Immunoglobulins, Thyroid-Stimulating/pharmacology; Lymphocytes/chemistry; Lymphocytes/immunology; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Myxedema/blood; Recombinant Proteins; Sequence Analysis, DNA; Thyrotropin/immunology

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Collection: 01-internacional Database: MEDLINE Main subject: Immunoglobulins, Thyroid-Stimulating / Hypothyroidism / Antibodies, Monoclonal / Myxedema Limits: Animals / Humans Language: En Journal: J Endocrinol Invest Year: 2003 Document type: Article

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