High-throughput simultaneous determination of plasma water deuterium and 18-oxygen enrichment using a high-temperature conversion elemental analyzer with isotope ratio mass spectrometry.

Richelle, M; Darimont, C; Piguet-Welsch, C; Fay, L B

Richelle, M; Darimont, C; Piguet-Welsch, C; Fay, L B.

Affiliation

Richelle M; Nestlé Research Center, Nestec, Ltd., P.O. Box 44, CH-1000 Lausanne 26, Switzerland. myriam.richelle@rdls.nestle.com

Rapid Commun Mass Spectrom ; 18(7): 795-8, 2004.

Article in En | MEDLINE | ID: mdl-15052562

Subject(s)

Blood; Deuterium/blood; Hot Temperature; Mass Spectrometry/methods; Oxygen/blood; Water/chemistry; Administration, Oral; Animals; Calibration; Deuterium/administration & dosage; Deuterium/pharmacokinetics; Male; Oxygen/administration & dosage; Oxygen/pharmacokinetics; Oxygen Isotopes; Rats; Rats, Sprague-Dawley; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Water/administration & dosage

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Collection: 01-internacional Database: MEDLINE Main subject: Oxygen / Mass Spectrometry / Blood / Water / Deuterium / Hot Temperature Type of study: Diagnostic_studies Limits: Animals Language: En Journal: Rapid Commun Mass Spectrom Year: 2004 Document type: Article

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