Development of a model based on body composition to predict drug kinetics; II. Application of the model to the use of digoxin in elderlies.

Ferrara, S; Pazzucconi, F; Bondioli, A; Mombelli, G; Agrati, A; Ferraro, G; Zoppi, F; De Rosa, C; Calabresi, L; Sirtori, C R

Ferrara, S; Pazzucconi, F; Bondioli, A; Mombelli, G; Agrati, A; Ferraro, G; Zoppi, F; De Rosa, C; Calabresi, L; Sirtori, C R.

Affiliation

Ferrara S; Department of Pharmacological Sciences, Grossi Paoletti Center, University of Milano, Via Balzaretti 9, 20133 Milan, Italy.

Pharmacol Res ; 50(1): 105-8, 2004 Jul.

Article in En | MEDLINE | ID: mdl-15082036

Subject(s)

Body Composition; Cardiotonic Agents/pharmacokinetics; Digoxin/pharmacokinetics; Pharmacokinetics; Aged; Blood Pressure/physiology; Cardiotonic Agents/blood; Cardiovascular Diseases/metabolism; Digoxin/blood; Electric Impedance; Electrocardiography; Female; Humans; Immunochemistry; Male; Models, Biological; Risk Factors

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Collection: 01-internacional Database: MEDLINE Main subject: Body Composition / Pharmacokinetics / Cardiotonic Agents / Digoxin Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male Language: En Journal: Pharmacol Res Year: 2004 Document type: Article

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