Sodium channel blocking activity of AM-36 and sipatrigine (BW619C89): in vitro and in vivo evidence.

Callaway, J K; Castillo-Melendez, M; Giardina, S F; Krstew, E K; Beart, P M; Jarrott, B

Callaway, J K; Castillo-Melendez, M; Giardina, S F; Krstew, E K; Beart, P M; Jarrott, B.

Affiliation

Callaway JK; Department of Physiology, Monash University, Clayton, Vic. 3800, Australia. j.callaway@hfi.unimelb.edu.au

Neuropharmacology ; 47(1): 146-55, 2004 Jul.

Article in En | MEDLINE | ID: mdl-15165842

Subject(s)

Piperazines/pharmacology; Pyrimidines/pharmacology; Sodium Channel Blockers/pharmacology; Sodium Channels/physiology; Synaptosomes/physiology; Animals; Batrachotoxins/pharmacology; Guinea Pigs; Male; Mice; Neuroprotective Agents/pharmacology; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface/antagonists & inhibitors; Receptors, Cell Surface/physiology; Receptors, Neurotransmitter/antagonists & inhibitors; Receptors, Neurotransmitter/physiology; Sodium Channels/drug effects; Synaptosomes/drug effects

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Collection: 01-internacional Database: MEDLINE Main subject: Piperazines / Pyrimidines / Synaptosomes / Sodium Channels / Sodium Channel Blockers Limits: Animals Language: En Journal: Neuropharmacology Year: 2004 Document type: Article

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