Differentiation of gut and hepatic first-pass loss of verapamil in intestinal and vascular access-ported (IVAP) rabbits.

Kunta, Jeevan R; Lee, Sung-Hack; Perry, Barbara A; Lee, Yong-Hee; Sinko, Patrick J

Kunta, Jeevan R; Lee, Sung-Hack; Perry, Barbara A; Lee, Yong-Hee; Sinko, Patrick J.

Affiliation

Kunta JR; Department of Pharmaceutics, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway 08854, USA.

Drug Metab Dispos ; 32(11): 1293-8, 2004 Nov.

Article in En | MEDLINE | ID: mdl-15304428

Subject(s)

Intestinal Mucosa/metabolism; Liver/metabolism; Verapamil/pharmacokinetics; Animals; Catheters, Indwelling; Female; Intestines/drug effects; Liver/drug effects; Metabolic Clearance Rate/drug effects; Metabolic Clearance Rate/physiology; Rabbits; Verapamil/pharmacology

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Collection: 01-internacional Database: MEDLINE Main subject: Verapamil / Intestinal Mucosa / Liver Type of study: Prognostic_studies Limits: Animals Language: En Journal: Drug Metab Dispos Year: 2004 Document type: Article

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