Stem cells and cancer; the polycomb connection.
Cell
; 118(4): 409-18, 2004 Aug 20.
Article
in En
| MEDLINE
| ID: mdl-15315754
ABSTRACT
Proteins from the Polycomb group (PcG) are epigenetic chromatin modifiers involved in cancer development and also in the maintenance of embryonic and adult stem cells. The therapeutic potential of stem cells and the growing conviction that tumors contain stem cells highlights the importance of understanding the extrinsic and intrinsic circuitry controlling stem cell fate and their connections to cancer.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Stem Cells
/
Neoplasms
Type of study:
Prognostic_studies
Limits:
Animals
/
Humans
Language:
En
Journal:
Cell
Year:
2004
Document type:
Article