Inhibitory effects of Centella asiatica on azoxymethane-induced aberrant crypt focus formation and carcinogenesis in the intestines of F344 rats.

Bunpo, P; Kataoka, K; Arimochi, H; Nakayama, H; Kuwahara, T; Bando, Y; Izumi, K; Vinitketkumnuen, U; Ohnishi, Y

Bunpo, P; Kataoka, K; Arimochi, H; Nakayama, H; Kuwahara, T; Bando, Y; Izumi, K; Vinitketkumnuen, U; Ohnishi, Y.

Affiliation

Bunpo P; Department of Molecular Bacteriology, Graduate School of Medicine, The University of Tokushima, Tokushima 770-8503, Japan.

Food Chem Toxicol ; 42(12): 1987-97, 2004 Dec.

Article in En | MEDLINE | ID: mdl-15500935

Subject(s)

Anticarcinogenic Agents; Azoxymethane/antagonists & inhibitors; Azoxymethane/toxicity; Carcinogens/toxicity; Centella/chemistry; Guanine/analogs & derivatives; Intestinal Neoplasms/prevention & control; Animals; Antimetabolites; Apoptosis/drug effects; Bromodeoxyuridine; Cell Proliferation/drug effects; Colon/drug effects; Colon/metabolism; DNA Methylation/drug effects; Diet; Guanine/metabolism; Intestinal Mucosa/cytology; Intestinal Mucosa/drug effects; Intestinal Neoplasms/chemically induced; Liver/drug effects; Liver/metabolism; Male; Plant Extracts/pharmacology; Rats; Rats, Inbred F344

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Collection: 01-internacional Database: MEDLINE Main subject: Azoxymethane / Carcinogens / Anticarcinogenic Agents / Centella / Guanine / Intestinal Neoplasms Limits: Animals Language: En Journal: Food Chem Toxicol Year: 2004 Document type: Article

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