A basic peptide within the juxtamembrane region is required for EGF receptor dimerization.

Aifa, Sami; Aydin, Jan; Nordvall, Gunnar; Lundström, Ingemar; Svensson, Samuel P S; Hermanson, Ola

Aifa, Sami; Aydin, Jan; Nordvall, Gunnar; Lundström, Ingemar; Svensson, Samuel P S; Hermanson, Ola.

Affiliation

Aifa S; Department of Pharmacology, Linköping University, SE-58185 Linköping, Sweden.

Exp Cell Res ; 302(1): 108-14, 2005 Jan 01.

Article in En | MEDLINE | ID: mdl-15541730

Subject(s)

Cell Membrane/metabolism; ErbB Receptors/chemistry; ErbB Receptors/metabolism; Membrane Proteins/metabolism; Amino Acid Sequence/physiology; Animals; COS Cells; Dimerization; ErbB Receptors/genetics; Humans; Intracellular Fluid/metabolism; Models, Molecular; Mutagenesis, Site-Directed; Mutation/genetics; Phosphorylation; Protein Structure, Tertiary/physiology; Receptor Protein-Tyrosine Kinases/metabolism; Sequence Deletion; Signal Transduction/physiology

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Collection: 01-internacional Database: MEDLINE Main subject: Cell Membrane / ErbB Receptors / Membrane Proteins Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Exp Cell Res Year: 2005 Document type: Article

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