Accelerated LV remodeling after myocardial infarction in TIMP-1-deficient mice: effects of exogenous MMP inhibition.

Ikonomidis, John S; Hendrick, Jennifer W; Parkhurst, Andrea M; Herron, Amanda R; Escobar, Patricia G; Dowdy, Kathryn B; Stroud, Robert E; Hapke, Elizabeth; Zile, Michael R; Spinale, Francis G

Ikonomidis, John S; Hendrick, Jennifer W; Parkhurst, Andrea M; Herron, Amanda R; Escobar, Patricia G; Dowdy, Kathryn B; Stroud, Robert E; Hapke, Elizabeth; Zile, Michael R; Spinale, Francis G.

Affiliation

Ikonomidis JS; Division of Cardiothoracic Surgery, Medical University of South Carolina, 114 Doughty St., Charleston, SC 29425, USA.

Am J Physiol Heart Circ Physiol ; 288(1): H149-58, 2005 Jan.

Article in En | MEDLINE | ID: mdl-15598866

Subject(s)

Hydroxamic Acids/pharmacology; Matrix Metalloproteinase Inhibitors; Myocardial Infarction/physiopathology; Oligopeptides/pharmacology; Tissue Inhibitor of Metalloproteinase-1/deficiency; Ventricular Remodeling/drug effects; Animals; Mice; Mice, Knockout; Myocardial Infarction/metabolism; Pressure; Stroke Volume; Time Factors

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Collection: 01-internacional Database: MEDLINE Main subject: Oligopeptides / Tissue Inhibitor of Metalloproteinase-1 / Ventricular Remodeling / Matrix Metalloproteinase Inhibitors / Hydroxamic Acids / Myocardial Infarction Limits: Animals Language: En Journal: Am J Physiol Heart Circ Physiol Year: 2005 Document type: Article

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