The structure of foot-and-mouth disease virus.
Curr Top Microbiol Immunol
; 288: 71-101, 2005.
Article
in En
| MEDLINE
| ID: mdl-15648175
ABSTRACT
Structural studies of foot-and-mouth disease virus (FMDV) have largely focused on the mature viral particle, providing atomic resolution images of the spherical protein capsid for a number of sero- and sub-types, structures of the highly immunogenic surface loop, Fab and GAG receptor complexes. Additionally, structures are available for a few non-structural proteins. The chapter reviews our current structural knowledge and its impact on our understanding of the virus life cycle proceeding from the mature virus through immune evasion/inactivation, cell-receptor binding and replication and alludes to future structural targets.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Foot-and-Mouth Disease Virus
Language:
En
Journal:
Curr Top Microbiol Immunol
Year:
2005
Document type:
Article