IL-6 signaling promotes tumor growth in colorectal cancer.

Becker, C; Fantini, M C; Wirtz, S; Nikolaev, A; Lehr, H A; Galle, P R; Rose-John, S; Neurath, M F

Becker, C; Fantini, M C; Wirtz, S; Nikolaev, A; Lehr, H A; Galle, P R; Rose-John, S; Neurath, M F.

Affiliation

Becker C; Lab. of Immunology, I. Medical Clinic, University of Mainz, Mainz, Germany.

Cell Cycle ; 4(2): 217-20, 2005 Feb.

Article in En | MEDLINE | ID: mdl-15655344

Subject(s)

Colorectal Neoplasms/pathology; Colorectal Neoplasms/physiopathology; Interleukin-6/physiology; Signal Transduction; Transforming Growth Factor beta/physiology; ADAM Proteins/genetics; ADAM Proteins/metabolism; ADAM17 Protein; Animals; Antineoplastic Agents/pharmacology; Antineoplastic Agents/therapeutic use; CD2 Antigens/genetics; CD2 Antigens/physiology; Cell Proliferation; Colorectal Neoplasms/drug therapy; Colorectal Neoplasms/genetics; Gene Expression Regulation/physiology; Gene Expression Regulation, Neoplastic; Interleukin-6/antagonists & inhibitors; Interleukin-6/genetics; Mice; Mice, Transgenic; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type II; Receptors, Interleukin-6/genetics; Receptors, Interleukin-6/metabolism; Receptors, Transforming Growth Factor beta/genetics; Receptors, Transforming Growth Factor beta/physiology; STAT3 Transcription Factor/genetics; STAT3 Transcription Factor/physiology; Signal Transduction/drug effects; Signal Transduction/genetics; T-Lymphocytes/pathology; Transforming Growth Factor beta/genetics

Search on Google

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Colorectal Neoplasms / Signal Transduction / Transforming Growth Factor beta / Interleukin-6 Type of study: Prognostic_studies Limits: Animals Language: En Journal: Cell Cycle Year: 2005 Document type: Article

Search on Google

XML

PubMed Links