Increased osteoblastogenesis and decreased bone resorption protect against ovariectomy-induced bone loss in thrombospondin-2-null mice.

Hankenson, K D; James, I E; Apone, S; Stroup, G B; Blake, S M; Liang, X; Lark, M W; Bornstein, P

Hankenson, K D; James, I E; Apone, S; Stroup, G B; Blake, S M; Liang, X; Lark, M W; Bornstein, P.

Affiliation

Hankenson KD; G161 400 N. Ingalls Bldg., Department of Orthopaedic Surgery, University of Michigan, Ann Arbor MI 48109, USA. kdhank@umich.edu

Matrix Biol ; 24(5): 362-70, 2005 Aug.

Article in En | MEDLINE | ID: mdl-15979292

Subject(s)

Bone Resorption/physiopathology; Osteoblasts/cytology; Osteogenesis/physiology; Ovariectomy/adverse effects; Thrombospondins/deficiency; Animals; Body Weight; Bone Density; Cell Differentiation; Estrogens/deficiency; Female; Femur/pathology; Femur/physiopathology; Mice; Mice, Knockout; Models, Animal; Thrombospondins/genetics; Thrombospondins/metabolism; Tibia/pathology; Tibia/physiopathology

Search on Google

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Osteoblasts / Osteogenesis / Bone Resorption / Ovariectomy / Thrombospondins Limits: Animals Language: En Journal: Matrix Biol Year: 2005 Document type: Article

Search on Google

XML

PubMed Links