Activation of p75NTR by proBDNF facilitates hippocampal long-term depression.

Woo, Newton H; Teng, Henry K; Siao, Chia-Jen; Chiaruttini, Cristina; Pang, Petti T; Milner, Teresa A; Hempstead, Barbara L; Lu, Bai

Woo, Newton H; Teng, Henry K; Siao, Chia-Jen; Chiaruttini, Cristina; Pang, Petti T; Milner, Teresa A; Hempstead, Barbara L; Lu, Bai.

Affiliation

Woo NH; Section on Neural Development and Plasticity, LCSN, NICHD, Porter Neuroscience Research Center, 35 Lincoln Drive, Bethesda, Maryland 20892-3714, USA.

Nat Neurosci ; 8(8): 1069-77, 2005 Aug.

Article in En | MEDLINE | ID: mdl-16025106

Subject(s)

Brain-Derived Neurotrophic Factor/pharmacology; Hippocampus/drug effects; Hippocampus/physiology; Long-Term Synaptic Depression/physiology; Protein Precursors/pharmacology; Receptors, Nerve Growth Factor/metabolism; Animals; Cells, Cultured; Dendrites/metabolism; Dendrites/ultrastructure; Hippocampus/metabolism; Hippocampus/ultrastructure; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Electron; Nerve Endings/metabolism; Nerve Endings/ultrastructure; Receptor, Nerve Growth Factor; Receptors, N-Methyl-D-Aspartate/metabolism; Receptors, Nerve Growth Factor/deficiency; Synaptic Transmission/drug effects; Synaptic Transmission/physiology

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Collection: 01-internacional Database: MEDLINE Main subject: Protein Precursors / Receptors, Nerve Growth Factor / Brain-Derived Neurotrophic Factor / Long-Term Synaptic Depression / Hippocampus Limits: Animals Language: En Journal: Nat Neurosci Year: 2005 Document type: Article

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