Regioselective enzymatic acylation of ribavirin to give potential multifunctional derivatives.

Liu, Bo-Kai; Wang, Na; Wu, Qi; Xie, Chuan-Ying; Lin, Xian-Fu

Liu, Bo-Kai; Wang, Na; Wu, Qi; Xie, Chuan-Ying; Lin, Xian-Fu.

Affiliation

Liu BK; Department of Chemistry, Zhejiang University, 310027, Hangzhou, P.R. China.

Biotechnol Lett ; 27(10): 717-20, 2005 May.

Article in En | MEDLINE | ID: mdl-16049740

Subject(s)

Candida/enzymology; Lipase/metabolism; Ribavirin/metabolism; Acetone/chemistry; Acylation; Alkenes/chemistry; Alkenes/metabolism; Butadienes/chemistry; Butadienes/metabolism; Chromatography, Thin Layer; Dicarboxylic Acids/chemistry; Dicarboxylic Acids/metabolism; Enzymes, Immobilized/chemistry; Enzymes, Immobilized/metabolism; Lipase/chemistry; Ribavirin/chemistry; Substrate Specificity

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Collection: 01-internacional Database: MEDLINE Main subject: Ribavirin / Candida / Lipase Language: En Journal: Biotechnol Lett Year: 2005 Document type: Article

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PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Ribavirin / Candida / Lipase Language: En Journal: Biotechnol Lett Year: 2005 Document type: Article