Zoledronate inhibits proliferation and induces apoptosis of imatinib-resistant chronic myeloid leukaemia cells.

Chuah, C; Barnes, D J; Kwok, M; Corbin, A; Deininger, M W N; Druker, B J; Melo, J V

Chuah, C; Barnes, D J; Kwok, M; Corbin, A; Deininger, M W N; Druker, B J; Melo, J V.

Affiliation

Chuah C; Imperial College London, Hammersmith Hospital, London, UK.

Leukemia ; 19(11): 1896-904, 2005 Nov.

Article in En | MEDLINE | ID: mdl-16167056

Subject(s)

Apoptosis/drug effects; Cell Proliferation/drug effects; Diphosphonates/pharmacology; Imidazoles/pharmacology; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/pathology; Antineoplastic Agents/pharmacology; Benzamides; Cell Cycle/drug effects; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Genes, abl/physiology; Humans; Imatinib Mesylate; Piperazines/pharmacology; Pyrimidines/pharmacology; Tumor Cells, Cultured; Zoledronic Acid

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Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Apoptosis / Cell Proliferation / Diphosphonates / Imidazoles Limits: Humans Language: En Journal: Leukemia Year: 2005 Document type: Article

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