O-demethylation of tramadol in the first months of life.

Allegaert, Karel; Van den Anker, J N; Verbesselt, R; de Hoon, J; Vanhole, C; Tibboel, D; Devlieger, H

Allegaert, Karel; Van den Anker, J N; Verbesselt, R; de Hoon, J; Vanhole, C; Tibboel, D; Devlieger, H.

Affiliation

Allegaert K; Neonatal Intensive Care Unit, Department of Paediatrics, University Hospital Gasthuisberg, Herestraat 49, 3000 Leuven, Belgium. karel.allegaert@uz.kuleuven.ac.be

Eur J Clin Pharmacol ; 61(11): 837-42, 2005 Dec.

Article in En | MEDLINE | ID: mdl-16283273

Subject(s)

Cytochrome P-450 CYP2D6/metabolism; Narcotics/metabolism; Tramadol/analogs & derivatives; Tramadol/metabolism; Aging/metabolism; Chromatography, High Pressure Liquid; Half-Life; Humans; Infant; Infant, Newborn; Linear Models; Narcotics/blood; Narcotics/urine; Tramadol/blood; Tramadol/urine

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Collection: 01-internacional Database: MEDLINE Main subject: Tramadol / Cytochrome P-450 CYP2D6 / Narcotics Type of study: Prognostic_studies Limits: Humans / Infant / Newborn Language: En Journal: Eur J Clin Pharmacol Year: 2005 Document type: Article

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