Spinocerebellar ataxia type 4 (SCA4): Initial pathoanatomical study reveals widespread cerebellar and brainstem degeneration.

Hellenbroich, Y; Gierga, K; Reusche, E; Schwinger, E; Deller, T; de Vos, R A I; Zühlke, C; Rüb, U

Hellenbroich, Y; Gierga, K; Reusche, E; Schwinger, E; Deller, T; de Vos, R A I; Zühlke, C; Rüb, U.

Affiliation

Hellenbroich Y; Department of Human Genetics, University of Lübeck, Lübeck, Germany.

J Neural Transm (Vienna) ; 113(7): 829-43, 2006 Jul.

Article in En | MEDLINE | ID: mdl-16362839

Subject(s)

Brain Stem/pathology; Cerebellum/pathology; Nerve Degeneration/pathology; Neurons/pathology; Spinocerebellar Ataxias/pathology; Aged; Auditory Diseases, Central/genetics; Auditory Diseases, Central/pathology; Auditory Diseases, Central/physiopathology; Brain Stem/physiopathology; Cerebellum/physiopathology; DNA Mutational Analysis; Deglutition Disorders/genetics; Deglutition Disorders/pathology; Deglutition Disorders/physiopathology; Female; Genotype; Germany; Humans; Immunohistochemistry; Male; Middle Aged; Mutation/genetics; Nerve Degeneration/physiopathology; Ocular Motility Disorders/genetics; Ocular Motility Disorders/pathology; Ocular Motility Disorders/physiopathology; Pedigree; Peptides/genetics; Sensation Disorders/genetics; Sensation Disorders/pathology; Sensation Disorders/physiopathology; Spinocerebellar Ataxias/genetics; Spinocerebellar Ataxias/physiopathology; Trinucleotide Repeat Expansion/genetics

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Collection: 01-internacional Database: MEDLINE Main subject: Brain Stem / Cerebellum / Spinocerebellar Ataxias / Nerve Degeneration / Neurons Limits: Aged / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: En Journal: J Neural Transm (Vienna) Year: 2006 Document type: Article

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