Collagen degradation by interleukin-1beta-stimulated gingival fibroblasts is accompanied by release and activation of multiple matrix metalloproteinases and cysteine proteinases.

Cox, S W; Eley, B M; Kiili, M; Asikainen, A; Tervahartiala, T; Sorsa, T

Cox, S W; Eley, B M; Kiili, M; Asikainen, A; Tervahartiala, T; Sorsa, T.

Affiliation

Cox SW; Department of Periodontology, Guy's, King's and St Thomas' Dental Institute, King's College London, UK. stephen.cox@kcl.ac.uk

Oral Dis ; 12(1): 34-40, 2006 Jan.

Article in En | MEDLINE | ID: mdl-16390466

Subject(s)

Collagen Type I/metabolism; Cysteine Endopeptidases/metabolism; Gingiva/enzymology; Matrix Metalloproteinases/metabolism; Periodontitis/enzymology; Adult; Blotting, Western; Cathepsin B/metabolism; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Female; Fibroblasts/drug effects; Fibroblasts/enzymology; Gingiva/cytology; Humans; Hydroxyproline/metabolism; Interleukin-1/pharmacology; Male; Middle Aged

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Collection: 01-internacional Database: MEDLINE Main subject: Periodontitis / Cysteine Endopeptidases / Matrix Metalloproteinases / Collagen Type I / Gingiva Type of study: Prognostic_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Oral Dis Year: 2006 Document type: Article

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