Specific polymorphisms of cytokine genes are associated with different risks to develop single-system or multi-system childhood Langerhans cell histiocytosis.

De Filippi, Paola; Badulli, Carla; Cuccia, Mariaclara; De Silvestri, Annalisa; Dametto, Ennia; Pasi, Annamaria; Garaventa, Alberto; del Prever, Adalberto Brach; Todesco, Alessandra; Trizzino, Antonino; Danesino, Cesare; Martinetti, Miryam; Aricò, Maurizio

De Filippi, Paola; Badulli, Carla; Cuccia, Mariaclara; De Silvestri, Annalisa; Dametto, Ennia; Pasi, Annamaria; Garaventa, Alberto; del Prever, Adalberto Brach; Todesco, Alessandra; Trizzino, Antonino; Danesino, Cesare; Martinetti, Miryam; Aricò, Maurizio.

Affiliation

De Filippi P; Genetica Medica, Università di Pavia and I.R.C.C.S. Policlinico San Matteo, Pavia, Italy.

Br J Haematol ; 132(6): 784-7, 2006 Mar.

Article in En | MEDLINE | ID: mdl-16487180

Subject(s)

Cytokines/genetics; Histiocytosis, Langerhans-Cell/genetics; Polymorphism, Single Nucleotide/genetics; Adolescent; Child; Child, Preschool; Female; Gene Frequency; Genotype; Humans; Infant; Interferon-gamma/genetics; Interleukin-1/genetics; Interleukin-4/genetics; Male; Point Mutation/genetics

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Collection: 01-internacional Database: MEDLINE Main subject: Histiocytosis, Langerhans-Cell / Cytokines / Polymorphism, Single Nucleotide Type of study: Etiology_studies / Risk_factors_studies Limits: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male Language: En Journal: Br J Haematol Year: 2006 Document type: Article

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