The polymorphism of multi-drug resistance 1 gene (MDR1) does not influence the pharmacokinetics of dexamethasone loaded into autologous erythrocytes of patients with inflammatory bowel disease.

Annese, V; Latiano, A; Rossi, L; Bossa, F; Damonte, G; Dallapiccola, B; Serafini, S; Pierigé, F; Andriulli, A; Magnani, M

Annese, V; Latiano, A; Rossi, L; Bossa, F; Damonte, G; Dallapiccola, B; Serafini, S; Pierigé, F; Andriulli, A; Magnani, M.

Affiliation

Annese V; Dipartimento di Medicina Generale e Specialistica, Unità di Gastroenterologia, Ospedale Casa Sollievo della Sofferenza Hospital, I.R.C.C.S., San Giovanni Rotondo, Italy.

Eur Rev Med Pharmacol Sci ; 10(1): 27-31, 2006.

Article in En | MEDLINE | ID: mdl-16494108

Subject(s)

Colitis, Ulcerative/genetics; Crohn Disease/genetics; Dexamethasone/analogs & derivatives; Genes, MDR/genetics; Prodrugs/pharmacokinetics; Adult; Colitis, Ulcerative/drug therapy; Colitis, Ulcerative/metabolism; Crohn Disease/drug therapy; Crohn Disease/metabolism; Dexamethasone/administration & dosage; Dexamethasone/blood; Dexamethasone/pharmacokinetics; Drug Carriers; Erythrocytes; Female; Humans; Male; Middle Aged; Polymorphism, Genetic; Prodrugs/administration & dosage

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Collection: 01-internacional Database: MEDLINE Main subject: Dexamethasone / Prodrugs / Colitis, Ulcerative / Crohn Disease / Genes, MDR Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Eur Rev Med Pharmacol Sci Year: 2006 Document type: Article

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