Inactivation of Wnt inhibitory factor-1 (WIF1) expression by epigenetic silencing is a common event in breast cancer.

Ai, Lingbao; Tao, Qian; Zhong, Sheng; Fields, C Robert; Kim, Wan-Ju; Lee, Michael W; Cui, Yan; Brown, Kevin D; Robertson, Keith D

Ai, Lingbao; Tao, Qian; Zhong, Sheng; Fields, C Robert; Kim, Wan-Ju; Lee, Michael W; Cui, Yan; Brown, Kevin D; Robertson, Keith D.

Affiliation

Ai L; Department of Biochemistry and Molecular Biology and UF-Shands Cancer Center Program in Cancer Genetics, Epigenetics and Tumor Virology, University of Florida College of Medicine, Gainesville, FL 32610, USA.

Carcinogenesis ; 27(7): 1341-8, 2006 Jul.

Article in En | MEDLINE | ID: mdl-16501252

Subject(s)

Breast Neoplasms/genetics; Carrier Proteins/biosynthesis; Carrier Proteins/genetics; Epigenesis, Genetic; Gene Silencing; Repressor Proteins/biosynthesis; Repressor Proteins/genetics; Adaptor Proteins, Signal Transducing; Cell Line, Tumor; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases/metabolism; DNA Methylation; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Male; Polymerase Chain Reaction; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; DNA Methyltransferase 3B

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Collection: 01-internacional Database: MEDLINE Main subject: Repressor Proteins / Breast Neoplasms / Carrier Proteins / Gene Silencing / Epigenesis, Genetic Type of study: Prognostic_studies Limits: Humans / Male Language: En Journal: Carcinogenesis Year: 2006 Document type: Article

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