Identification of COMT and ErmC inhibitors by using a microplate assay in combination with library focusing by virtual screening.

Kreander, K; Kurkela, M; Siiskonen, A; Vuorela, P; Tammela, P

Kreander, K; Kurkela, M; Siiskonen, A; Vuorela, P; Tammela, P.

Affiliation

Kreander K; Drug Discovery and Development Technology Center (DDTC), Faculty of Pharmacy, University of Helsinki, Finland.

Pharmazie ; 61(3): 247-8, 2006 Mar.

Article in En | MEDLINE | ID: mdl-16599271

Subject(s)

Catechol O-Methyltransferase Inhibitors; Catechols/antagonists & inhibitors; Enzyme Inhibitors/pharmacology; Computer Simulation; Dimethyl Sulfoxide/pharmacology; Drug Design; Drug Evaluation, Preclinical; Models, Molecular; Structure-Activity Relationship

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Collection: 01-internacional Database: MEDLINE Main subject: Catechols / Enzyme Inhibitors / Catechol O-Methyltransferase Inhibitors Type of study: Diagnostic_studies / Screening_studies Language: En Journal: Pharmazie Year: 2006 Document type: Article

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