Telomerase inhibition with a novel G-quadruplex-interactive agent, telomestatin: in vitro and in vivo studies in acute leukemia.

Tauchi, T; Shin-ya, K; Sashida, G; Sumi, M; Okabe, S; Ohyashiki, J H; Ohyashiki, K

Tauchi, T; Shin-ya, K; Sashida, G; Sumi, M; Okabe, S; Ohyashiki, J H; Ohyashiki, K.

Affiliation

Tauchi T; First Department of Internal Medicine, Tokyo Medical University, Shinjuku-ku, Tokyo, Japan. tauchi@tokyo-med.ac.jp

Oncogene ; 25(42): 5719-25, 2006 Sep 21.

Article in En | MEDLINE | ID: mdl-16652154

Subject(s)

Leukemia/drug therapy; Oxazoles/pharmacology; Telomerase/antagonists & inhibitors; Acute Disease; Animals; Antineoplastic Agents/pharmacology; GTP-Binding Proteins/drug effects; GTP-Binding Proteins/metabolism; Humans; Kinetics; Transplantation, Heterologous; U937 Cells

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Collection: 01-internacional Database: MEDLINE Main subject: Oxazoles / Leukemia / Telomerase Limits: Animals / Humans Language: En Journal: Oncogene Year: 2006 Document type: Article

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