Breast cancer-specific mRNA transcripts presence in peripheral blood after adjuvant chemotherapy predicts poor survival among high-risk breast cancer patients treated with high-dose chemotherapy with peripheral blood stem cell support.

Quintela-Fandino, Miguel; López, Joaquín Martínez; Hitt, Ricardo; Gamarra, Soledad; Jimeno, Antonio; Ayala, Rosa; Hornedo, Javier; Guzman, Cecilia; Gilsanz, Florinda; Cortés-Funes, Hernán

Quintela-Fandino, Miguel; López, Joaquín Martínez; Hitt, Ricardo; Gamarra, Soledad; Jimeno, Antonio; Ayala, Rosa; Hornedo, Javier; Guzman, Cecilia; Gilsanz, Florinda; Cortés-Funes, Hernán.

Affiliation

Quintela-Fandino M; Medical Oncology Department, University Hospital 12 de Octubre, Madrid, Spain. quintelamiguel2000@yahoo.es

J Clin Oncol ; 24(22): 3611-8, 2006 Aug 01.

Article in En | MEDLINE | ID: mdl-16877728

Subject(s)

Antineoplastic Combined Chemotherapy Protocols/therapeutic use; Biomarkers, Tumor/blood; Breast Neoplasms/genetics; Breast Neoplasms/pathology; Peripheral Blood Stem Cell Transplantation; RNA Precursors/blood; Adult; Aged; Antigens, Surface/genetics; Antineoplastic Combined Chemotherapy Protocols/administration & dosage; Breast Neoplasms/blood; Breast Neoplasms/chemistry; Breast Neoplasms/therapy; Calcium-Binding Proteins/genetics; Carboplatin/administration & dosage; Chemotherapy, Adjuvant; Cyclophosphamide/administration & dosage; Doxorubicin/administration & dosage; Epirubicin/administration & dosage; Epithelial Cell Adhesion Molecule; Female; Fluorouracil/administration & dosage; Follow-Up Studies; Humans; Keratins/genetics; Membrane Proteins/genetics; Middle Aged; Multivariate Analysis; Odds Ratio; Paclitaxel/administration & dosage; Predictive Value of Tests; Presenilin-2; Prognosis; RNA, Messenger; RNA, Neoplasm; Receptor, ErbB-2/genetics; Retrospective Studies; Reverse Transcriptase Polymerase Chain Reaction; Risk Assessment; Risk Factors; Survival Analysis; Thiotepa/administration & dosage; Treatment Outcome

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Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / RNA Precursors / Antineoplastic Combined Chemotherapy Protocols / Biomarkers, Tumor / Peripheral Blood Stem Cell Transplantation Type of study: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Language: En Journal: J Clin Oncol Year: 2006 Document type: Article

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