Enhanced patient serum immunoreactivity to recombinant Mycobacterium tuberculosis CFP32 produced in the yeast Pichia pastoris compared to Escherichia coli and its potential for serodiagnosis of tuberculosis.

Benabdesselem, Chaouki; Fathallah, Dahmani M; Huard, Richard C; Zhu, Hongxia; Jarboui, Mohamed Ali; Dellagi, Koussay; Ho, John L; Barbouche, Ridha M

Benabdesselem, Chaouki; Fathallah, Dahmani M; Huard, Richard C; Zhu, Hongxia; Jarboui, Mohamed Ali; Dellagi, Koussay; Ho, John L; Barbouche, Ridha M.

Affiliation

Benabdesselem C; Laboratory of Immunopathology, Vaccinology, and Molecular Genetics, Institut Pasteur de Tunis, Tunis, Tunisia.

J Clin Microbiol ; 44(9): 3086-93, 2006 Sep.

Article in En | MEDLINE | ID: mdl-16954231

Subject(s)

Antibodies, Bacterial/blood; Bacterial Proteins/immunology; Pichia/metabolism; Recombinant Proteins/immunology; Tuberculosis, Pulmonary/diagnosis; Antigens, Bacterial/genetics; Antigens, Bacterial/immunology; Antigens, Bacterial/metabolism; Bacterial Proteins/genetics; Bacterial Proteins/metabolism; Escherichia coli/genetics; Escherichia coli/metabolism; Humans; Mycobacterium tuberculosis/immunology; Pichia/genetics; Recombinant Proteins/metabolism; Sensitivity and Specificity; Serologic Tests; Tuberculosis, Pulmonary/immunology; Tuberculosis, Pulmonary/microbiology

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Full text: 1 Collection: 01-internacional Health context: 3_ND Database: MEDLINE Main subject: Pichia / Bacterial Proteins / Tuberculosis, Pulmonary / Recombinant Proteins / Antibodies, Bacterial Type of study: Diagnostic_studies / Evaluation_studies Limits: Humans Language: En Journal: J Clin Microbiol Year: 2006 Document type: Article

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