[Diagnosis and therapy of Rhodococcus equi infection in the horse]. / De diagnostiek en therapeutische mogelijkheden van een Rhodococcus equi infectie bij het paard.
Tijdschr Diergeneeskd
; 131(17): 602-11, 2006 Sep 01.
Article
in Nl
| MEDLINE
| ID: mdl-16989420
Infection with Rhodococcus equi is an important cause of pneumonia in foals, but other organ systems may also be affected. The intracellular presence of R. equi and the formation of granulomatous and suppurative inflammatory tissue mean that prolonged treatment is needed. The pharmacological properties of the combination of erythromycin and rifampicin have improved the survival of foals infected with R. equi; however, erythromycin can cause adverse reactions in foals and mares, which has prompted the search for alternative therapies. The combination of azithromycin or clarithromycin with rifampicin seems to be a promising alternative. However these combinations are expensive and adverse effects remain to be determined, especially in the dams of treated foals. Thus correct diagnosis and appropriate use of drugs are essential for the treatment of R. equi infection in foals.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Actinomycetales Infections
/
Rhodococcus equi
/
Pneumonia, Bacterial
/
Horse Diseases
/
Anti-Bacterial Agents
Type of study:
Diagnostic_studies
Limits:
Animals
Language:
Nl
Journal:
Tijdschr Diergeneeskd
Year:
2006
Document type:
Article