A novel E3 ubiquitin ligase substrate screen identifies Rho guanine dissociation inhibitor as a substrate of gene related to anergy in lymphocytes.

Su, Leon; Lineberry, Neil; Huh, Yul; Soares, Luis; Fathman, C Garrison

Su, Leon; Lineberry, Neil; Huh, Yul; Soares, Luis; Fathman, C Garrison.

Affiliation

Su L; Department of Medicine, Division of Immunology and Rheumatology, Stanford University, Stanford, CA 94305, USA.

J Immunol ; 177(11): 7559-66, 2006 Dec 01.

Article in En | MEDLINE | ID: mdl-17114425

Subject(s)

Biological Assay/methods; Escherichia coli/genetics; Genetic Vectors; Guanine Nucleotide Dissociation Inhibitors/metabolism; Ubiquitin-Protein Ligases/metabolism; Cell Line; Enzyme Activation/physiology; Humans; Interleukin-2/biosynthesis; Plasmids; Reverse Transcriptase Polymerase Chain Reaction; T-Lymphocytes/metabolism; Transfection; rho Guanine Nucleotide Dissociation Inhibitor alpha; rho-Specific Guanine Nucleotide Dissociation Inhibitors

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Collection: 01-internacional Health context: 3_ND Database: MEDLINE Main subject: Biological Assay / Guanine Nucleotide Dissociation Inhibitors / Ubiquitin-Protein Ligases / Escherichia coli / Genetic Vectors Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Immunol Year: 2006 Document type: Article

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