Methylsulfonylmethane (MSM) ingestion causes a significant resonance in proton magnetic resonance spectra of brain and cerebrospinal fluid.
Neuropediatrics
; 37(5): 312-4, 2006 Oct.
Article
in En
| MEDLINE
| ID: mdl-17236113
ABSTRACT
The use of methylsulfonylmethane (MSM), available as an "over-the-counter" dietary supplement, led to the occurrence of an abnormal resonance at 3.15 ppm in the in vivo brain proton MR spectrum as well as the in vitro cerebrospinal fluid NMR study of a 4-year-old girl. The concentration of this compound amounted to 1.2 mmol/l in brain tissue and 1.7 mmol/l in cerebrospinal fluid. Our findings illustrate that ingestion of exogenous compounds, e.g., in medication, food or "innocent" supplements, may lead to abnormal resonances in spectroscopy studies that might be difficult to assign.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Sulfones
/
Brain
/
Magnetic Resonance Spectroscopy
/
Cerebrospinal Fluid
/
Dimethyl Sulfoxide
Type of study:
Etiology_studies
Limits:
Child
/
Child, preschool
/
Female
/
Humans
/
Male
Language:
En
Journal:
Neuropediatrics
Year:
2006
Document type:
Article