Disruption of friend of GATA 2 gene (FOG-2) by a de novo t(8;10) chromosomal translocation is associated with heart defects and gonadal dysgenesis.

Finelli, P; Pincelli, A I; Russo, S; Bonati, M T; Recalcati, M P; Masciadri, M; Giardino, D; Cavagnini, F; Larizza, L

Finelli, P; Pincelli, A I; Russo, S; Bonati, M T; Recalcati, M P; Masciadri, M; Giardino, D; Cavagnini, F; Larizza, L.

Affiliation

Finelli P; Laboratory of Medical Cytogenetics and Molecular Genetics, Istituto Auxologico Italiano, Milan, Italy. finelli@auxologico.it

Clin Genet ; 71(3): 195-204, 2007 Mar.

Article in En | MEDLINE | ID: mdl-17309641

Subject(s)

Chromosomes, Human, Pair 10; Chromosomes, Human, Pair 8; DNA-Binding Proteins/genetics; Gonadal Dysgenesis/genetics; Heart Septal Defects, Atrial/genetics; Transcription Factors/genetics; Translocation, Genetic; Amino Acid Sequence; Child; DNA-Binding Proteins/chemistry; Humans; Karyotyping; Male; Sequence Deletion; Transcription Factors/chemistry

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Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Translocation, Genetic / Chromosomes, Human, Pair 8 / Chromosomes, Human, Pair 10 / DNA-Binding Proteins / Gonadal Dysgenesis / Heart Septal Defects, Atrial Type of study: Prognostic_studies / Risk_factors_studies Limits: Child / Humans / Male Language: En Journal: Clin Genet Year: 2007 Document type: Article

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