[High-dose immunoglobulin during pregnancy for two patients with risk of recurrent neonatal haemochromatosis]. / Traitement par immunoglobulines pendant la grossesse chez deux patientes à risque de récurrence d'hémochromatose néonatale.

ABSTRACT

Two patients, with prior affected children with Neonatal Haemochromatosis [NH], benefited from intravenous immunoglobulin treatment during their following pregnancy in order to prevent recurrent NH. Whereas NH is a severe disease with high risk of recurrence and high mortality rate (about 80%), a recent treatment was suggested in the USA, which seems to completely modify the prognosis of this pathology. We proposed this treatment for two patients with indeed apparent benefit, giving birth to two healthy babies.