Metabolism of (-)-fenchone by CYP2A6 and CYP2B6 in human liver microsomes.

Miyazawa, M; Gyoubu, K

Miyazawa, M; Gyoubu, K.

Affiliation

Miyazawa M; Department of Applied Chemistry, Faculty of Science and Engineering, Kinki University, Osaka, Japan. miyazawa@apch.kindai.ac.jp

Xenobiotica ; 37(2): 194-204, 2007 Feb.

Article in En | MEDLINE | ID: mdl-17484521

Subject(s)

Aryl Hydrocarbon Hydroxylases/metabolism; Microsomes, Liver/enzymology; Mixed Function Oxygenases/metabolism; Norbornanes/metabolism; Oxidoreductases, N-Demethylating/metabolism; Biotransformation; Camphanes; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP2B6; Gas Chromatography-Mass Spectrometry; Humans; Hydroxylation; In Vitro Techniques; Kinetics; Norbornanes/chemistry; Norbornanes/pharmacokinetics; Recombinant Proteins/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Oxidoreductases, N-Demethylating / Microsomes, Liver / Aryl Hydrocarbon Hydroxylases / Mixed Function Oxygenases / Norbornanes Limits: Humans Language: En Journal: Xenobiotica Year: 2007 Document type: Article

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