Phylogenetic groups and virulence factors of Escherichia coli strains causing pyelonephritis in children with and without urinary tract abnormalities.
Clin Microbiol Infect
; 13(7): 740-2, 2007 Jul.
Article
in En
| MEDLINE
| ID: mdl-17488325
ABSTRACT
Escherichia coli isolates causing acute pyelonephritis in 93 children (25% with urinary tract abnormalities) were tested for nine virulence factors (papC, papGII, papGIII, sfa/foc, hlyC, cnf1, iucC, fyuA and iroN) and their phylogenetic groups were determined. Isolates lacking papGII were more frequent among patients with urinary tract abnormalities (58% vs. 10%, p 0.0003), as were non-virulent phylogenetic group A isolates (25% vs. 5%, p 0.043). Pyelonephritis caused by less virulent E. coli strains was more frequent among patients with significant urinary tract abnormalities. Further studies are required to determine whether screening for E. coli virulence factors may help to identify children warranting anatomical investigations.
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Collection:
01-internacional
Health context:
3_ND
Database:
MEDLINE
Main subject:
Phylogeny
/
Pyelonephritis
/
Urinary Tract
/
Virulence Factors
/
Escherichia coli
Type of study:
Prognostic_studies
Limits:
Adolescent
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Language:
En
Journal:
Clin Microbiol Infect
Year:
2007
Document type:
Article