PEFG (cisplatin, epirubicin, 5-fluorouracil, gemcitabine) for patients with advanced pancreatic cancer: the ghost regimen.
Cancer Lett
; 256(1): 25-8, 2007 Oct 18.
Article
in En
| MEDLINE
| ID: mdl-17561341
ABSTRACT
The consensus report of the International Society of Gastrointestinal Oncology on the therapeutic management of advanced pancreatic cancer is commented. In the context of the available literature, a critical and methodological analysis supporting the role of cisplatin, epirubicin, 5- fluorouracil, gemcitabine (PEFG) regimen in the treatment of unresectable and metastatic pancreatic cancer is provided. In particular, the clinical relevance of the outcome observed in the phase III trial comparing PEFG regimen to standard gemcitabine is highlighted. Results of other recent trials comparing gemcitabine-erlotinib, gemcitabine-capecitabine and gemcitabine-oxaliplatin combinations to single agent gemcitabine are briefly commented from a clinical perspective.
Search on Google
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pancreatic Neoplasms
/
Adenocarcinoma
/
Antineoplastic Combined Chemotherapy Protocols
Limits:
Humans
Language:
En
Journal:
Cancer Lett
Year:
2007
Document type:
Article