Mitochondrial role in ischemia-reperfusion of rat hearts exposed to high-K+ cardioplegia and clonazepam: energetic and contractile consequences.

Consolini, A E; Ragone, M I; Conforti, P; Volonté, M G

Consolini, A E; Ragone, M I; Conforti, P; Volonté, M G.

Affiliation

Consolini AE; Cátedra de Farmacología y, Departamento de Ciencias Biológicas, Facultad de Ciencias Exactas, Universidad Nacional de La Plata, 47y 115 (1900) La Plata, Argentina. dinamia@biol.unlp.edu.ar

Can J Physiol Pharmacol ; 85(5): 483-96, 2007 May.

Article in En | MEDLINE | ID: mdl-17632582

Subject(s)

Clonazepam/pharmacology; Mitochondria/physiology; Myocardial Reperfusion Injury/physiopathology; Potassium/pharmacology; Adenosine Triphosphate/metabolism; Animals; Anticonvulsants/pharmacology; Caffeine/pharmacology; Calcium/metabolism; Cardioplegic Solutions/pharmacology; Chromatography, High Pressure Liquid; Diastole/drug effects; Diastole/physiology; Energy Metabolism/drug effects; Female; Heart/drug effects; Heart/physiopathology; Heart Arrest, Induced/methods; Male; Myocardial Contraction/drug effects; Myocardial Reperfusion Injury/metabolism; Myocardium/metabolism; Phosphocreatine/metabolism; Rats; Rats, Sprague-Dawley; Sarcoplasmic Reticulum/drug effects; Sarcoplasmic Reticulum/metabolism; Ventricular Function, Left/drug effects; Ventricular Function, Left/physiology

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Collection: 01-internacional Database: MEDLINE Main subject: Potassium / Myocardial Reperfusion Injury / Clonazepam / Mitochondria Limits: Animals Language: En Journal: Can J Physiol Pharmacol Year: 2007 Document type: Article

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