Catecholaminergic neuronal loss in locus coeruleus of aged female dtg APP/PS1 mice.

O'Neil, Jahn N; Mouton, Peter R; Tizabi, Yousef; Ottinger, Mary Ann; Lei, De-Liang; Ingram, Donald K; Manaye, Kebreten F

O'Neil, Jahn N; Mouton, Peter R; Tizabi, Yousef; Ottinger, Mary Ann; Lei, De-Liang; Ingram, Donald K; Manaye, Kebreten F.

Affiliation

O'Neil JN; Department of Physiology & Biophysics, College of Medicine, Howard University, Washington, DC 20059, United States.

J Chem Neuroanat ; 34(3-4): 102-7, 2007 Nov.

Article in En | MEDLINE | ID: mdl-17658239

Subject(s)

Aging/pathology; Alzheimer Disease/pathology; Nerve Degeneration/pathology; Neurons/pathology; Tyrosine 3-Monooxygenase/metabolism; Amyloid beta-Protein Precursor/genetics; Animals; Catecholamines/metabolism; Disease Models, Animal; Female; Humans; Immunohistochemistry; Locus Coeruleus/metabolism; Locus Coeruleus/pathology; Mice; Mice, Transgenic; Mutation; Nerve Degeneration/metabolism; Neurons/metabolism; Presenilin-1/genetics; Substantia Nigra/metabolism; Substantia Nigra/pathology; Ventral Tegmental Area/metabolism; Ventral Tegmental Area/pathology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tyrosine 3-Monooxygenase / Aging / Alzheimer Disease / Nerve Degeneration / Neurons Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: J Chem Neuroanat Year: 2007 Document type: Article

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