Changes in expression of steroid receptors, their downstream target genes and their associated co-regulators during the sequential acquisition of tamoxifen resistance in vitro.

Scott, D J; Parkes, A T; Ponchel, F; Cummings, M; Poola, I; Speirs, V

Scott, D J; Parkes, A T; Ponchel, F; Cummings, M; Poola, I; Speirs, V.

Affiliation

Scott DJ; Leeds Institute of Molecular Medicine, University of Leeds, Leeds, UK.

Int J Oncol ; 31(3): 557-65, 2007 Sep.

Article in En | MEDLINE | ID: mdl-17671682

Subject(s)

Antineoplastic Agents, Hormonal/pharmacology; Drug Screening Assays, Antitumor; Gene Expression Regulation, Neoplastic; Receptors, Steroid/metabolism; Tamoxifen/analogs & derivatives; Cell Cycle; Cell Line, Tumor; Cell Proliferation; DNA Primers/chemistry; Estrogen Antagonists/pharmacology; Estrogen Receptor alpha/metabolism; Estrogen Receptor beta/metabolism; Humans; Oligonucleotide Array Sequence Analysis; Prohibitins; RNA, Messenger/metabolism; Tamoxifen/pharmacology

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Collection: 01-internacional Database: MEDLINE Main subject: Tamoxifen / Drug Screening Assays, Antitumor / Receptors, Steroid / Gene Expression Regulation, Neoplastic / Antineoplastic Agents, Hormonal Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Int J Oncol Year: 2007 Document type: Article

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