Neurotrophin-mediated neuroprotection of hippocampal neurons following traumatic brain injury is not associated with acute recovery of hippocampal function.

Royo, N C; LeBold, D; Magge, S N; Chen, I; Hauspurg, A; Cohen, A S; Watson, D J

Royo, N C; LeBold, D; Magge, S N; Chen, I; Hauspurg, A; Cohen, A S; Watson, D J.

Affiliation

Royo NC; Department of Neurosurgery, 371A Stemmler Hall/6071, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA. nicolas_royo@hotmail.com

Neuroscience ; 148(2): 359-70, 2007 Aug 24.

Article in En | MEDLINE | ID: mdl-17681695

Subject(s)

Brain Injuries/drug therapy; Hippocampus/pathology; Nerve Growth Factors/therapeutic use; Neurons/drug effects; Neuroprotective Agents/therapeutic use; Animals; Association Learning/drug effects; Behavior, Animal/drug effects; Brain Injuries/pathology; Cell Count/methods; Disease Models, Animal; Dose-Response Relationship, Radiation; Electric Stimulation/methods; Evoked Potentials/drug effects; Evoked Potentials/radiation effects; Hippocampus/physiopathology; In Vitro Techniques; Male; Motor Activity/drug effects; Neurons/physiology; Rats; Rats, Sprague-Dawley; Recovery of Function/drug effects; Recovery of Function/physiology; Time Factors

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Injuries / Neuroprotective Agents / Hippocampus / Nerve Growth Factors / Neurons Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals Language: En Journal: Neuroscience Year: 2007 Document type: Article

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