West Nile virus capsid protein induces p53-mediated apoptosis via the sequestration of HDM2 to the nucleolus.

Yang, Mi-Ran; Lee, Sung Ryul; Oh, Wonkyung; Lee, Eun-Woo; Yeh, Jung-Yong; Nah, Jin-Ju; Joo, Yi-Seok; Shin, Jaekyoon; Lee, Han-Woong; Pyo, Suhkneung; Song, Jaewhan

Yang, Mi-Ran; Lee, Sung Ryul; Oh, Wonkyung; Lee, Eun-Woo; Yeh, Jung-Yong; Nah, Jin-Ju; Joo, Yi-Seok; Shin, Jaekyoon; Lee, Han-Woong; Pyo, Suhkneung; Song, Jaewhan.

Affiliation

Yang MR; Department of Food Science and Biotechnology, Sungkyunkwan University, Suwon 440-746, Korea.

Cell Microbiol ; 10(1): 165-76, 2008 Jan.

Article in En | MEDLINE | ID: mdl-17697133

Subject(s)

Apoptosis; Capsid Proteins/metabolism; Cell Nucleolus/chemistry; Proto-Oncogene Proteins c-mdm2/metabolism; Tumor Suppressor Protein p53/metabolism; West Nile virus/physiology; Animals; Cell Line; Cells, Cultured; Chlorocebus aethiops; Fibroblasts/virology; Humans; Mice; Protein Binding; bcl-2-Associated X Protein/biosynthesis

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: West Nile virus / Cell Nucleolus / Tumor Suppressor Protein p53 / Apoptosis / Capsid Proteins / Proto-Oncogene Proteins c-mdm2 Limits: Animals / Humans Language: En Journal: Cell Microbiol Year: 2008 Document type: Article

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