Targeting human medulloblastoma: oncolytic virotherapy with myxoma virus is enhanced by rapamycin.

Lun, Xue Qing; Zhou, Hongyuan; Alain, Tommy; Sun, Beichen; Wang, Limei; Barrett, John W; Stanford, Marianne M; McFadden, Grant; Bell, John; Senger, Donna L; Forsyth, Peter A

Lun, Xue Qing; Zhou, Hongyuan; Alain, Tommy; Sun, Beichen; Wang, Limei; Barrett, John W; Stanford, Marianne M; McFadden, Grant; Bell, John; Senger, Donna L; Forsyth, Peter A.

Affiliation

Lun XQ; Department of Oncology, Tom Baker Cancer Centre, University of Calgary, Calgary, Alberta, Canada.

Cancer Res ; 67(18): 8818-27, 2007 Sep 15.

Article in En | MEDLINE | ID: mdl-17875723

Subject(s)

Antibiotics, Antineoplastic/pharmacology; Medulloblastoma/therapy; Myxoma virus/physiology; Oncolytic Virotherapy/methods; Sirolimus/pharmacology; Animals; Combined Modality Therapy; Enzyme Activation/drug effects; Humans; Injections, Intralesional; Medulloblastoma/drug therapy; Medulloblastoma/virology; Mice; Mice, Nude; NIH 3T3 Cells; Neoplasm Metastasis; Oncogene Protein v-akt/metabolism; Virus Replication/drug effects; Xenograft Model Antitumor Assays

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sirolimus / Oncolytic Virotherapy / Medulloblastoma / Antibiotics, Antineoplastic / Myxoma virus Limits: Animals / Humans Language: En Journal: Cancer Res Year: 2007 Document type: Article

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