The functional R620W variant of the PTPN22 gene is associated with celiac disease.

Santin, I; Castellanos-Rubio, A; Aransay, A M; Castaño, L; Vitoria, J C; Bilbao, J R

Santin, I; Castellanos-Rubio, A; Aransay, A M; Castaño, L; Vitoria, J C; Bilbao, J R.

Affiliation

Santin I; Immunogenetics Laboratory, Endocrinology and Diabetes Research Group, Hospital de Cruces, Barakaldo, Bizkaia, Spain.

Tissue Antigens ; 71(3): 247-9, 2008 Mar.

Article in En | MEDLINE | ID: mdl-18194365

Subject(s)

Celiac Disease/genetics; Polymorphism, Single Nucleotide; Protein Tyrosine Phosphatase, Non-Receptor Type 22/genetics; Adolescent; Adult; Amino Acid Substitution; Case-Control Studies; Celiac Disease/enzymology; Celiac Disease/immunology; Child; Child, Preschool; Female; Gene Frequency; Genetic Predisposition to Disease; Genetic Variation; Genotype; Humans; Immune Tolerance/genetics; Infant; Male; Protein Tyrosine Phosphatase, Non-Receptor Type 22/immunology; Risk Factors; Spain

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Celiac Disease / Polymorphism, Single Nucleotide / Protein Tyrosine Phosphatase, Non-Receptor Type 22 Type of study: Etiology_studies / Observational_studies / Risk_factors_studies Limits: Adolescent / Adult / Child / Child, preschool / Female / Humans / Infant / Male Country/Region as subject: Europa Language: En Journal: Tissue Antigens Year: 2008 Document type: Article

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