Involvement of the BLT2 receptor in the itch-associated scratching induced by 12-(S)-lipoxygenase products in ICR mice.

Kim, H J; Kim, D K; Kim, H; Koh, J Y; Kim, K M; Noh, M S; Lee, S; Kim, S; Park, S H; Kim, J J; Kim, S Y; Lee, C H

Kim, H J; Kim, D K; Kim, H; Koh, J Y; Kim, K M; Noh, M S; Lee, S; Kim, S; Park, S H; Kim, J J; Kim, S Y; Lee, C H.

Affiliation

Kim HJ; Laboratory of Skin Research AmorePacific Corporation R&D Center, Gyeonggi-do, Korea.

Br J Pharmacol ; 154(5): 1073-8, 2008 Jul.

Article in En | MEDLINE | ID: mdl-18536755

Subject(s)

Arachidonate 12-Lipoxygenase/metabolism; Behavior, Animal; Pruritus/metabolism; Receptors, Leukotriene B4/metabolism; 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid/metabolism; Animals; Antipruritics/pharmacology; Behavior, Animal/drug effects; Capsaicin/pharmacology; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical/methods; Fatty Alcohols/pharmacology; Glycols/pharmacology; Male; Mice; Mice, Inbred ICR; Naltrexone/pharmacology; Pruritus/chemically induced; Pruritus/prevention & control; Receptors, Leukotriene B4/drug effects; Signal Transduction/drug effects; Tetrazoles/pharmacology; Video Recording

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pruritus / Behavior, Animal / Arachidonate 12-Lipoxygenase / Receptors, Leukotriene B4 Type of study: Risk_factors_studies Limits: Animals Language: En Journal: Br J Pharmacol Year: 2008 Document type: Article

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