Autologous bone marrow transplantation in secondary acute monoblastic leukemia following Hodgkin's disease.
Bone Marrow Transplant
; 7 Suppl 3: 131-2, 1991.
Article
in En
| MEDLINE
| ID: mdl-1855076
ABSTRACT
Acute non lymphocytic leukemia (AnLL) is the most common second malignancy (SM) in survivors of childhood Hodgkin's Disease (HD). Chemotherapy responsiveness is usually poor and death ensues briefly after diagnosis. We report the case of a 13 year-old girl, affected by HD, stage IV, mixed cellularity, who developed AnLL one year after the HD treatment was stopped. Autologous Bone Marrow Transplantation (ABMT) was performed 9 months after complete remission (CR) was achieved by chemotherapy. Presently, the patient is alive and on continues CR, 3 years and 7 months after ABMT. ABMT may be a promising approach for secondary AnLL, the prognosis of which is almost invariably fatal with conventional chemotherapy.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Hodgkin Disease
/
Leukemia, Monocytic, Acute
/
Bone Marrow Transplantation
Type of study:
Prognostic_studies
Limits:
Adolescent
/
Female
/
Humans
Language:
En
Journal:
Bone Marrow Transplant
Year:
1991
Document type:
Article